DegronMD - Q69YN4(VIRMA)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R1741H	SIDM00407	B-Cell Non-Hodgkin's Lymphoma	GDSC	NRGPLPPLR	DEG_APCC_DBOX_1	1748:1756	Mutation rewiring degron network	0.1389
p.R1741H	SIDM01154	T-Lymphoblastic Leukemia	GDSC	NRGPLPPLR	DEG_APCC_DBOX_1	1748:1756	Mutation rewiring degron network	0.1389
p.R1741H	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	NRGPLPPLR	DEG_APCC_DBOX_1	1748:1756	Mutation rewiring degron network	0.1389
p.R1770H	SIDM00718	Non-Small Cell Lung Carcinoma	GDSC	PLSST	DEG_SPOP_SBC_1	1757:1761	Mutation rewiring degron network	0.0833
p.R1770H	NCI-H358	lung	COSMIC	PLSST	DEG_SPOP_SBC_1	1757:1761	Mutation rewiring degron network	0.0833
p.R1764C	SIDM00892	Breast Carcinoma	GDSC	NRGPLPPLR	DEG_APCC_DBOX_1	1748:1756	Mutation rewiring degron network	0.1111
p.R1764C	SIDM00892	Breast Carcinoma	GDSC	PLSST	DEG_SPOP_SBC_1	1757:1761	Mutation rewiring degron network	0.25
p.R1764C	BT-483	breast	COSMIC	NRGPLPPLR	DEG_APCC_DBOX_1	1748:1756	Mutation rewiring degron network	0.1111
p.R1764C	BT-483	breast	COSMIC	PLSST	DEG_SPOP_SBC_1	1757:1761	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons