DegronMD - Q6B0I6(KDM4D)

KDM4D

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S430T	TCGA-23-1029	OV	TCGA	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation altering degron motif	0.6005
p.S430T	DO28571	OV	ICGC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation altering degron motif	0.6005
p.T432S	TCGA-A1-A0SO	BRCA	TCGA	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation altering degron motif	0.7116
p.T432S	DO2020	BRCA	ICGC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation altering degron motif	0.7116
p.G438C	TCGA-D3-A2JP	SKCM	TCGA	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.2778
p.G438C	DO47407	SKCM	ICGC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.2778
p.S435F	TCGA-JW-A5VL	CESC	TCGA	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation altering degron motif	0.6871
p.S435F	DO49976	CESC	ICGC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation altering degron motif	0.6871
p.I444S	TCGA-VQ-A8P5	STAD	TCGA	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.1111
p.I444S	DO51763	STAD	ICGC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.1111
p.V423A	DO8858	COAD	ICGC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.1667
p.R419L	SIDM00521	Small Cell Lung Carcinoma	GDSC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.0556
p.R419L	ACH-000743	Lung Cancer	CCLE	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.0556
p.R419L	COR-L95	lung	COSMIC	PSSTPSST	DEG_SCF_FBW7_1	429:436	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc