DegronMD - Q6FHJ7(SFRP4)

SFRP4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S241C	TCGA-A8-A09G	BRCA	TCGA	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389
p.S241C	DO1990	BRCA	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389
p.S241Y	TCGA-AP-A056	UCEC	TCGA	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389
p.S241Y	TCGA-BS-A0UV	UCEC	TCGA	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389
p.S241Y	DO42793	UCEC	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389
p.S241Y	DO43971	UCEC	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389
p.R262H	TCGA-B5-A11E	UCEC	TCGA	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.R262H	TCGA-HD-7832	HNSC	TCGA	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.R262H	DO16061	HNSC	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.R262H	DO41644	UCEC	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.R262C	TCGA-N9-A4Q7	UCS	TCGA	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.R262S	DO229019	LICA	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.P246Q	DO229022	LICA	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.2778
p.P246S	DO231057	LUSC	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.2778
p.S241F	DO222363	MELA	ICGC	ILPHQD	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc