DegronMD - Q6IPR3(TYW3)

TYW3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D244V	TCGA-64-5781	LUAD	TCGA	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation rewiring degron network	0.1111
p.F255I	TCGA-86-8673	LUAD	TCGA	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation altering degron motif	0.7415
p.D247Y	TCGA-98-8021	LUSC	TCGA	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation rewiring degron network	0.1944
p.Y259D	TCGA-BR-8680	STAD	TCGA	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation rewiring degron network	0.2778
p.D258N	SIDM00587	Biliary Tract Carcinoma	GDSC	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation rewiring degron network	0.3056
p.D258N	SIDM00500	Colorectal Carcinoma	GDSC	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation rewiring degron network	0.3056
p.D258N	HuCCT1	biliary tract	COSMIC	VTIFPE	LIG_APCC_ABBA_1	252:257	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc