DegronMD - Q6KB66(KRT80)

KRT80

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P20S	TCGA-FR-A726	SKCM	TCGA	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation altering degron motif	0.6752
p.P20S	DO48665	SKCM	ICGC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation altering degron motif	0.6752
p.S29L	TCGA-S5-AA26	BLCA	TCGA	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation blocking phosphorylation signal	0.6111
p.S29L	DO51904	BLCA	ICGC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation blocking phosphorylation signal	0.6111
p.S29L	SIDM00494	Non-Small Cell Lung Carcinoma	GDSC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation blocking phosphorylation signal	0.6111
p.S29L	ACH-000528	Lung Cancer	CCLE	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation blocking phosphorylation signal	0.6111
p.S29L	ABC-1	lung	COSMIC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation blocking phosphorylation signal	0.6111
p.R25Q	DO227979	COCA	ICGC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation rewiring degron network	0.2778
p.R25Q	DO222765	COCA	ICGC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation rewiring degron network	0.2778
p.R25Q	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation rewiring degron network	0.2778
p.R25Q	SIDM00736	Non-Cancerous	GDSC	VTPVGS	DEG_SCF_FBW7_1	18:23	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc