DegronMD - Q6NSW7(NANOGP8)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S56C	SIDM00557	Neuroblastoma	GDSC	PDSST	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0556
p.L60P	SIDM00893	Breast Carcinoma	GDSC	PDSST	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1667
p.L60P	BT-20	breast	COSMIC	PDSST	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1667
p.P66L	SIDM01587	Bladder Carcinoma	GDSC	PDSST	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7582
p.M58I	KM12	large intestine	COSMIC	PDSST	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons