DegronMD - Q6NV75(GPR153)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G535R	DO222623	BTCA	ICGC	PTPPSS	DEG_SCF_FBW7_1	538:543	Mutation rewiring degron network	0.25
p.P552S	SIDM00875	Breast Carcinoma	GDSC	PTPPSS	DEG_SCF_FBW7_1	538:543	Mutation rewiring degron network	0.0833
p.P552S	SIDM00257	Neuroblastoma	GDSC	PTPPSS	DEG_SCF_FBW7_1	538:543	Mutation rewiring degron network	0.0833
p.E536A	ACH-000612	Lymphoma	CCLE	PTPPSS	DEG_SCF_FBW7_1	538:543	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons