DegronMD - Q6NVH7(SWSAP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L38I	TCGA-EO-A22R	UCEC	TCGA	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.25
p.L38I	DO42713	UCEC	ICGC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.25
p.G31R	TCGA-J8-A3YG	THCA	TCGA	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0556
p.G31R	DO39835	THCA	ICGC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0556
p.Q34K	TCGA-VQ-A91D	STAD	TCGA	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.1389
p.Q34K	DO51783	STAD	ICGC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.1389
p.R42L	DO229253	THCA	ICGC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.8428
p.L45F	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6981
p.L45F	SIDM00879	Breast Carcinoma	GDSC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6981
p.L45F	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6981
p.L45F	SIDM00032	Bladder Carcinoma	GDSC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6981
p.L45F	SIDM00068	Colorectal Carcinoma	GDSC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6981
p.L45F	SIDM00785	Acute Myeloid Leukemia	GDSC	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6981
p.E32G	ACH-000264	Lung Cancer	CCLE	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0833
p.E32G	ACH-000581	Gastric Cancer	CCLE	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0833
p.E32G	ACH-000894	Lung Cancer	CCLE	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0833
p.E32G	ACH-002291	Embryonal Cancer	CCLE	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0833
p.L38F	ACH-002048	Sarcoma	CCLE	TRRPLQSMP	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.25

Kaplan plot for SWSAP1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SWSAP1

UniProt ID: Q6NVH7

Entrez ID: 126074

Protein name: ATPase SWSAP1 (SWIM-type zinc finger 7-associated protein 1) (SWS1-associated protein 1) (ZSWIM7-associated protein 1) (ZSWIM7AP1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SWSAP1 in