TAF2
UniProt ID: Q6P1X5
Entrez ID: 6873
Protein name: Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly ...
FUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473, PubMed:9418870, PubMed:9774672). TAF2 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF1 (PubMed:9774672, PubMed:33795473). {ECO:0000269|PubMed:33795473, ECO:0000269|PubMed:9418870, ECO:0000269|PubMed:9774672}.
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GO - Biological processes (BP):
G2/M transition of mitotic cell cycle [GO:0000086]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription, D...
G2/M transition of mitotic cell cycle [GO:0000086]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation from RNA polymerase II promoter [GO:0006367]
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GO - Molecular function (MF):
chromatin binding [GO:0003682]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription cis-regulatory region binding [GO:0000976]...
chromatin binding [GO:0003682]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription cis-regulatory region binding [GO:0000976]
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GO - Cellular component (CC):
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276]...
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276]
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TAF2
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Kaplan plot for TAF2 in
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*NOTE: the Kaplan plots were collected from OncoLnc