DegronMD - Q6P4F1(FUT10)

FUT10

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R432L	TCGA-09-2044	OV	TCGA	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation altering degron motif	0.7316
p.R440L	TCGA-66-2800	LUSC	TCGA	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation rewiring degron network	0.25
p.R432W	TCGA-D7-8576	STAD	TCGA	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation altering degron motif	0.7523
p.S440L	DO219061	BLCA	ICGC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation rewiring degron network	0.25
p.A428V	DO23224	LINC	ICGC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation rewiring degron network	0.2778
p.R435M	DO45311	LUAD	ICGC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation altering degron motif	0.8632
p.R435S	DO45311	LUAD	ICGC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation altering degron motif	0.7427
p.R435K	DO51276	SKCM	ICGC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation altering degron motif	0.7237
p.F444L	DO41133	UCEC	ICGC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation rewiring degron network	0.1389
p.S445C	SIDM01220	Glioma	GDSC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation rewiring degron network	0.1111
p.S445C	LNZTA3WT4	central nervous system	COSMIC	PLRTPPLS	DEG_SCF_FBW7_1	430:437	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc