DegronMD - Q6P5X7(TMEM71)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q6E	TCGA-05-4397	LUAD	TCGA	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.3056
p.Q6E	TCGA-AR-A250	BRCA	TCGA	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.3056
p.Q6E	TCGA-GV-A3JZ	BLCA	TCGA	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.3056
p.Q6E	DO773	BLCA	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.3056
p.Q6E	DO1802	BRCA	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.3056
p.Q6E	DO25320	LUAD	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.3056
p.R3Q	TCGA-B5-A0JY	UCEC	TCGA	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.R3Q	TCGA-SW-A7EB	STAD	TCGA	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.R3Q	DO220895	MELA	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.R3Q	DO50143	STAD	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.R3Q	DO43041	UCEC	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.G24R	DO222494	MELA	ICGC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.0556
p.R3L	SIDM00660	Colorectal Carcinoma	GDSC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.R3L	ACH-000985	Colon/Colorectal Cancer	CCLE	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222
p.R3L	LS-411N	large intestine	COSMIC	LMSTPVAS	DEG_SCF_FBW7_1	7:14	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons