DegronMD - Q6P9F7(LRRC8B)

LRRC8B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S196L	TCGA-C5-A1BE	CESC	TCGA	DSGKQS	DEG_SCF_TRCP1_1	200:205	Mutation rewiring degron network	0.2222
p.S196L	DO49006	CESC	ICGC	DSGKQS	DEG_SCF_TRCP1_1	200:205	Mutation rewiring degron network	0.2222
p.S191L	TCGA-W3-A828	SKCM	TCGA	DSGKQS	DEG_SCF_TRCP1_1	200:205	Mutation rewiring degron network	0.0833
p.S191L	DO51273	SKCM	ICGC	DSGKQS	DEG_SCF_TRCP1_1	200:205	Mutation rewiring degron network	0.0833
p.I199T	TCGA-ZG-A9NI	PRAD	TCGA	DSGKQS	DEG_SCF_TRCP1_1	200:205	Mutation rewiring degron network	0.3056
p.I199T	DO219448	PRAD	ICGC	DSGKQS	DEG_SCF_TRCP1_1	200:205	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc