DegronMD - Q6PML9(SLC30A9)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M305K	TCGA-77-A5G1	LUSC	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.1111
p.M305K	DO50096	LUSC	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.1111
p.H298Y	TCGA-A8-A09A	BRCA	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.3056
p.H298Y	DO2955	BRCA	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.3056
p.R306C	TCGA-AA-A01R	COAD	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.R306C	TCGA-BH-A0HA	BRCA	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.R306C	DO1658	BRCA	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.R306C	DO7934	COAD	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.R306C	SIDM01127	Non-Small Cell Lung Carcinoma	GDSC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.R306C	ACH-000628	Lung Cancer	CCLE	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.R306C	NCI-H596	lung	COSMIC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0833
p.P299L	TCGA-AJ-A3BG	UCEC	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.2778
p.P299L	DO42633	UCEC	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.2778
p.G281V	TCGA-AX-A1CE	UCEC	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0556
p.G281V	DO42280	UCEC	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0556
p.H298R	TCGA-EE-A3JI	SKCM	TCGA	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.3056
p.H298R	DO47268	SKCM	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.3056
p.Y307H	DO222877	COCA	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation rewiring degron network	0.0556
p.D295V	DO36556	READ	ICGC	VQTPDPS	DEG_SCF_FBW7_1	291:297	Mutation altering degron motif	0.6674

Kaplan plot for SLC30A9 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SLC30A9

UniProt ID: Q6PML9

Entrez ID: 10463

Protein name: Zinc transporter 9 (ZnT-9) (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SLC30A9 in