DegronMD - Q6UWD8(C16orf54)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L201F	TCGA-BH-A0HF	BRCA	TCGA	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.2778
p.L201F	DO1749	BRCA	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.2778
p.W214R	TCGA-D3-A8GM	SKCM	TCGA	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.25
p.W214R	DO50288	SKCM	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.25
p.R204W	TCGA-EJ-5505	PRAD	TCGA	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.8634
p.R204W	DO36337	PRAD	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.8634
p.R219Q	TCGA-ER-A42L	SKCM	TCGA	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.1111
p.R219Q	DO223910	SKCM	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.1111
p.E208K	TCGA-FW-A3R5	SKCM	TCGA	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.591
p.E208K	DO228471	BRCA	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.591
p.E208K	DO37406	SKCM	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.591
p.Q202L	TCGA-UB-A7MB	LIHC	TCGA	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.3056
p.Q202L	DO52318	LIHC	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.3056
p.R204Q	DO23500	LINC	ICGC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.7329
p.V205I	SIDM01943	Colorectal Carcinoma	GDSC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation altering degron motif	0.5965
p.P197H	SIDM00781	Colorectal Carcinoma	GDSC	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.1667
p.P197H	ACH-001199	Colon/Colorectal Cancer	CCLE	PRVTLEQIS	DEG_APCC_DBOX_1	203:211	Mutation rewiring degron network	0.1667

Kaplan plot for C16orf54 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C16orf54

UniProt ID: Q6UWD8

Entrez ID: 283897

Protein name: Transmembrane protein C16orf54

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for C16orf54 in