DegronMD - Q6UWJ8(CD164L2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P119L	TCGA-BT-A20V	BLCA	TCGA	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.2222
p.P119L	DO689	BLCA	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.2222
p.P128T	TCGA-EE-A3AD	SKCM	TCGA	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.5919
p.P128T	DO37707	SKCM	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.5919
p.P115H	TCGA-FS-A1ZP	SKCM	TCGA	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.1111
p.P115H	DO37703	SKCM	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.1111
p.A115E	DO14159	HNSC	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.1111
p.T123K	DO228986	LICA	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.7306
p.P129T	DO229022	LICA	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.7031
p.L123I	DO229022	LICA	ICGC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.7174
p.E131D	SIDM01293	Colorectal Carcinoma	GDSC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.5647
p.S134G	SIDM00789	Colorectal Carcinoma	GDSC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.2778
p.S134G	ACH-000997	Colon/Colorectal Cancer	CCLE	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.2778
p.S134G	HCT-15	large intestine	COSMIC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.2778
p.A132T	SIDM01007	T-Lymphoblastic Leukemia	GDSC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.7139
p.A132T	ACH-002256	Leukemia	CCLE	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.7139
p.A132T	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.7139
p.G125E	SIDM00003	Melanoma	GDSC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.6087
p.G125E	M14	skin	COSMIC	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation altering degron motif	0.6087
p.Y117S	ACH-001541	Myeloma	CCLE	TTGSPPVPEA	DEG_COP1_1	123:132	Mutation rewiring degron network	0.1667

Kaplan plot for CD164L2 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CD164L2

UniProt ID: Q6UWJ8

Entrez ID: 388611

Protein name: CD164 sialomucin-like 2 protein

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for CD164L2 in