DegronMD - Q6UX41(BTNL8)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V398I	TCGA-12-1092	GBM	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.0833
p.V398I	TCGA-E2-A15O	BRCA	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.0833
p.V398I	TCGA-EY-A215	UCEC	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.0833
p.C415S	TCGA-35-4122	LUAD	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.25
p.F421I	TCGA-55-8092	LUAD	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.0833
p.P400S	TCGA-D3-A8GI	SKCM	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.1389
p.P400S	TCGA-EE-A2MS	SKCM	TCGA	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.1389
p.C415G	SIDM00863	Burkitt's Lymphoma	GDSC	IGVFLD	LIG_APCC_ABBA_1	407:412	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons