DegronMD - Q6UXG3(CD300LG)

CD300LG

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A102V	TCGA-A5-A0G2	UCEC	TCGA	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.0556
p.A102V	DO41235	UCEC	ICGC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.0556
p.K76Q	TCGA-E6-A1LX	UCEC	TCGA	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation substituting flanking lysine	0.2222
p.K76Q	DO41020	UCEC	ICGC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation substituting flanking lysine	0.2222
p.T98I	TCGA-W3-AA1W	SKCM	TCGA	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.1667
p.T98I	DO51277	SKCM	ICGC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.1667
p.R85H	DO227802	COCA	ICGC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation altering degron motif	0.8244
p.R85H	SIDM01133	Other Solid Cancers	GDSC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation altering degron motif	0.8244
p.S84C	DO228278	LICA	ICGC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation altering degron motif	0.643
p.L97I	SIDM01144	Gastric Carcinoma	GDSC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.1944
p.L97I	ACH-000303	Gastric Cancer	CCLE	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.1944
p.L97I	NCI-SNU-5	stomach	COSMIC	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.1944
p.A102P	ACH-000868	Lung Cancer	CCLE	SRQELSLIV	DEG_APCC_DBOX_1	84:92	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc