DegronMD - Q6Y2X3(DNAJC14)

DNAJC14

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E482Q	TCGA-44-2662	LUAD	TCGA	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.0833
p.E482Q	DO26290	LUAD	ICGC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.0833
p.N475S	TCGA-55-8204	LUAD	TCGA	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.2778
p.N475S	DO45322	LUAD	ICGC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.2778
p.V470A	SIDM01154	T-Lymphoblastic Leukemia	GDSC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation altering degron motif	0.6936
p.V470A	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation altering degron motif	0.6936
p.E481D	SIDM00282	Colorectal Carcinoma	GDSC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.1111
p.E481D	CW-2	large intestine	COSMIC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.1111
p.A462V	SIDM00901	Endometrial Carcinoma	GDSC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.1667
p.A462V	AN3-CA	endometrium	COSMIC	VMVHPD	LIG_APCC_ABBA_1	468:473	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc