DegronMD - Q6ZN44(UNC5A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V127M	TCGA-86-8668	LUAD	TCGA	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation rewiring degron network	0.3056
p.V127M	DO228583	GACA	ICGC	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation rewiring degron network	0.3056
p.V127M	DO25669	LUAD	ICGC	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation rewiring degron network	0.3056
p.S132L	TCGA-B5-A11Y	UCEC	TCGA	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation altering degron motif	0.7667
p.S132L	DO40889	UCEC	ICGC	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation altering degron motif	0.7667
p.S132L	SIDM01451	Pancreatic Carcinoma	GDSC	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation altering degron motif	0.7667
p.S132L	ACH-000933	Pancreatic Cancer	CCLE	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation altering degron motif	0.7667
p.W129L	DO228974	LICA	ICGC	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation altering degron motif	0.5904
p.A140S	DO229038	LICA	ICGC	AWSSS	DEG_SPOP_SBC_1	128:132	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons