DegronMD - Q6ZR37(PLEKHG7)

PLEKHG7

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E14K	TCGA-C8-A26Y	BRCA	TCGA	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.1667
p.E14K	DO1273	BRCA	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.1667
p.L36F	TCGA-E2-A1B5	BRCA	TCGA	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.1111
p.L36F	DO3299	BRCA	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.1111
p.L16I	TCGA-F5-6814	READ	TCGA	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.2222
p.L16I	DO36556	READ	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.2222
p.L16F	TCGA-FW-A3R5	SKCM	TCGA	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.2222
p.L16F	DO37406	SKCM	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.2222
p.A26G	DO223048	ESCA	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation altering degron motif	0.754
p.L31V	DO233030	GACA	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.25
p.D18Y	DO225400	LAML	ICGC	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.2778
p.Q11H	ACH-001991	Primary	CCLE	PRPSLRSLP	DEG_APCC_DBOX_1	20:28	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc