DegronMD - Q6ZRC1(C4orf50)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N149K	DO52708	CLLE	ICGC	LAPGVPETSHHLDV	DEG_ODPH_VHL_1	130:143	Mutation rewiring degron network	0.1667
p.G123R	DO50970	LICA	ICGC	LAPGVPETSHHLDV	DEG_ODPH_VHL_1	130:143	Mutation rewiring degron network	0.1389
p.S147N	DO50970	LICA	ICGC	LAPGVPETSHHLDV	DEG_ODPH_VHL_1	130:143	Mutation rewiring degron network	0.2222
p.S131N	DO232761	PBCA	ICGC	LAPGVPETSHHLDV	DEG_ODPH_VHL_1	130:143	Mutation altering degron motif	0.7069
p.N136S	DO218848	SKCA	ICGC	LAPGVPETSHHLDV	DEG_ODPH_VHL_1	130:143	Mutation altering degron motif	0.7069

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons