DegronMD - Q6ZS11(RINL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N24D	DO230334	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.25
p.N24D	DO229010	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.25
p.N24D	DO229013	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.25
p.N24D	DO229016	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.25
p.N24D	DO229003	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.25
p.N24D	DO229005	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.25
p.V17I	DO230342	COCA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.0556
p.R42H	DO233855	GACA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.1389
p.E34A	DO18899	KIRC	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation altering degron motif	0.7701
p.A26E	DO229037	LICA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.3056
p.P19T	DO229041	LICA	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.1111
p.H35N	DO26949	LUSC	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation altering degron motif	0.7423
p.D37N	DO47569	SKCM	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.2778
p.L18M	DO41572	UCEC	ICGC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.0833
p.R42C	ACH-000986	Colon/Colorectal Cancer	CCLE	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.1389
p.P26S	HuP-T3	pancreas	COSMIC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.3056
p.D37G	CW-2	large intestine	COSMIC	DRTPLGVLS	DEG_APCC_DBOX_1	27:35	Mutation rewiring degron network	0.2778

Kaplan plot for RINL in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RINL

UniProt ID: Q6ZS11

Entrez ID: 126432

Protein name: Ras and Rab interactor-like protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RINL in