DegronMD - Q6ZTQ4(CDHR3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V447F	TCGA-86-8281	LUAD	TCGA	PPYY	ITCH	438:441	Mutation rewiring degron network	0.1667
p.T428M	TCGA-B5-A11N	UCEC	TCGA	PPYY	ITCH	438:441	Mutation rewiring degron network	0.0556
p.Y446H	TCGA-B5-A1MX	UCEC	TCGA	PPYY	ITCH	438:441	Mutation rewiring degron network	0.1944
p.V445I	TCGA-EO-A22T	UCEC	TCGA	PPYY	ITCH	438:441	Mutation rewiring degron network	0.2222
p.L450I	SIDM00683	Prostate Carcinoma	GDSC	PPYY	ITCH	438:441	Mutation rewiring degron network	0.0833
p.L450I	ACH-000977	lymph node	CCLE	PPYY	ITCH	438:441	Mutation rewiring degron network	0.0833
p.L450I	LNCaP-Clone-FGC	prostate	COSMIC	PPYY	ITCH	438:441	Mutation rewiring degron network	0.0833
p.V447I	SIDM01011	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPYY	ITCH	438:441	Mutation rewiring degron network	0.1667
p.A437G	SIDM00045	Gastric Carcinoma	GDSC	PPYY	ITCH	438:441	Mutation rewiring degron network	0.3056
p.G431R	MDA-MB-436	breast	COSMIC	PPYY	ITCH	438:441	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons