DegronMD - Q6ZTR5(CFAP47)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D1458E	SIDM00871	Non-Cancerous	GDSC	LPPYQD	LIG_APCC_ABBA_1	1453:1458	Mutation altering degron motif	0.5647
p.D1458E	SIDM00872	Breast Carcinoma	GDSC	LPPYQD	LIG_APCC_ABBA_1	1453:1458	Mutation altering degron motif	0.5647
p.D1458V	SIDM00528	Breast Carcinoma	GDSC	LPPYQD	LIG_APCC_ABBA_1	1453:1458	Mutation altering degron motif	0.7785

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons