DegronMD - Q6ZTW0(TPGS1)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T18M	DO222718	COCA	ICGC	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation rewiring degron network	0.3056
p.A29V	DO233855	GACA	ICGC	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation rewiring degron network	0.1944
p.S20T	SIDM00987	Thyroid Gland Carcinoma	GDSC	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation altering degron motif	0.7116
p.S20T	ACH-000191	Thyroid Cancer	CCLE	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation altering degron motif	0.7116
p.P12L	SIDM00923	Cervical Carcinoma	GDSC	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation rewiring degron network	0.1389
p.P12L	ACH-001336	Cervical Cancer	CCLE	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation rewiring degron network	0.1389
p.A15S	ACH-000395	Lung Cancer	CCLE	DSGRQS	DEG_SCF_TRCP1_1	19:24	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons