DegronMD - Q6ZU64(CFAP65)

CFAP65

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E1804K	SIDM00331	B-Lymphoblastic Leukemia	GDSC	IGPTPQPE	DEG_SCF_FBW7_2	1814:1821	Mutation rewiring degron network	0.0556
p.V1733L	SIDM00018	Acute Myeloid Leukemia	GDSC	VPSSS	DEG_SPOP_SBC_1	1733:1737	Mutation altering degron motif	0.6765
p.V1733L	KO52	haematopoietic and lymphoid tissue	COSMIC	VPSSS	DEG_SPOP_SBC_1	1733:1737	Mutation altering degron motif	0.6765
p.L1725R	SIDM00118	Colorectal Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	1733:1737	Mutation rewiring degron network	0.1111
p.L1725R	HCC2998	large intestine	COSMIC	VPSSS	DEG_SPOP_SBC_1	1733:1737	Mutation rewiring degron network	0.1111
p.Q1829H	SIDM01503	Small Cell Lung Carcinoma	GDSC	IGPTPQPE	DEG_SCF_FBW7_2	1814:1821	Mutation rewiring degron network	0.1111
p.Q1819P	SIDM01608	Endometrial Carcinoma	GDSC	IGPTPQPE	DEG_SCF_FBW7_2	1814:1821	Mutation altering degron motif	0.5924

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*NOTE: the Kaplan plots were collected from OncoLnc