DegronMD - Q6ZUT1(NKAPD1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D130G	SIDM00664	Pancreatic Carcinoma	GDSC	VKSST	DEG_SPOP_SBC_1	140:144	Mutation rewiring degron network	0.0556
p.D130G	Hs766T	pancreas	COSMIC	VKSST	DEG_SPOP_SBC_1	140:144	Mutation rewiring degron network	0.0556
p.T247N	SIDM01090	Colorectal Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	234:238	Mutation substituting flanking lysine	0.1944
p.T247N	RKO	large intestine	COSMIC	ASSSS	DEG_SPOP_SBC_1	234:238	Mutation substituting flanking lysine	0.1944
p.R45Q	SIDM00781	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R45Q	SIDM00431	T-Lymphoblastic Leukemia	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R45Q	SIDM00780	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R45Q	MOLT-16	haematopoietic and lymphoid tissue	COSMIC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R45Q	SNU-C2B	large intestine	COSMIC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R45W	SIDM00009	Acute Myeloid Leukemia	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R45W	SIDM01013	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.R60C	SIDM00217	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.25
p.R60C	SNU-1040	large intestine	COSMIC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.25
p.R58W	SIDM01394	Kidney Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.3056
p.K178N	EW-11	bone	COSMIC	ADSSS	DEG_SPOP_SBC_1	181:185	Mutation rewiring degron network	0.25
p.T246N	RKO	large intestine	COSMIC	ASSSS	DEG_SPOP_SBC_1	234:238	Mutation rewiring degron network	0.1111

Kaplan plot for NKAPD1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NKAPD1

UniProt ID: Q6ZUT1

Entrez ID: 55216

Protein name: Uncharacterized protein NKAPD1 (NKAP domain containing protein 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NKAPD1 in