DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
CFAP20DC
UniProt ID:
Q6ZVT6
Entrez ID:
200844
Protein name:
Protein CFAP20DC (Uncharacterized protein C3orf67)
External links:
UniprotKB
HGNC
RefSeq
COSMIC
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Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
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GO - Biological processes (BP):
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GO - Molecular function (MF):
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GO - Cellular component (CC):
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CFAP20DC
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AAchange
Cancer
Sample
Mutation type
Dataset
Degron hit
Class
E3 ligase
Source protein
Location
Detail
Mutation
Sample
Cancer
Degron hit
Class
Location
Dataset
Mutation
Sample
Cancer
Dataset
Degron hit
Class
Location
Type
Impact score
p.H213N
SIDM01611
Endometrial Carcinoma
GDSC
NKENI
DEG_APCC_KENBOX_2
199:203
Mutation rewiring degron network
0.0556
Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for CFAP20DC in
Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc