DegronMD

Uniprot ID: Q6ZVT6

Source protein: Protein CFAP20DC

Source gene: CFAP20DC

Class: DEG_APCC_KENBOX_2

Location: 199:203

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9919

ASA_SCORE: 103.88

COIL: 0.6814

CONS_SCORE: 0.3661

DSS_SCORE: 0.6463

HELIX: 0.2756

FCONS_SCORE: 1.1191

RIG_SCORE: 0.6702

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.H213N	SIDM01611	Endometrial Carcinoma	GDSC	NKENI	DEG_APCC_KENBOX_2	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P42684	Tyrosine-protein kinase ABL2	DEG_APCC_KENBOX_2	588:592	NKENI	APC,CDC20,FZR1	0.8172	More...
Q96GX5	Serine/threonine-protein kinase greatwall	DEG_APCC_KENBOX_2	505:509	NKENI	APC,CDC20,FZR1	0.7264	More...
Q99700	Ataxin-2	DEG_APCC_KENBOX_2	762:766	NKENI	APC,CDC20,FZR1	0.9963	More...
Q9NYC9	Dynein axonemal heavy chain 9	DEG_APCC_KENBOX_2	3229:3233	NKENI	APC,CDC20,FZR1	0.5274	More...
Q6ZVT6	Protein CFAP20DC	DEG_APCC_KENBOX_2	199:203	NKENI	APC,CDC20,FZR1	0.9919	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons