STXBP4
UniProt ID: Q6ZWJ1
Entrez ID: 252983
Protein name: Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disru...
FUNCTION: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity). {ECO:0000250}.
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GO - Biological processes (BP):
cellular response to DNA damage stimulus [GO:0006974]; cellular response to interferon-gamma [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein st...
cellular response to DNA damage stimulus [GO:0006974]; cellular response to interferon-gamma [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of glucose transmembrane transport [GO:0010827]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]
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GO - Molecular function (MF):
syntaxin binding [GO:0019905]...
syntaxin binding [GO:0019905]
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GO - Cellular component (CC):
cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; phagocytic vesicle [GO:0045335]...
cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; phagocytic vesicle [GO:0045335]
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STXBP4
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Kaplan plot for STXBP4 in
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*NOTE: the Kaplan plots were collected from OncoLnc