DegronMD - Q6ZWL3(CYP4V2)

CYP4V2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R296C	TCGA-AJ-A23O	UCEC	TCGA	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation altering degron motif	0.719
p.R296C	DO43290	UCEC	ICGC	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation altering degron motif	0.719
p.R296C	SIDM00181	Bladder Carcinoma	GDSC	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation altering degron motif	0.719
p.R296C	SIDM01646	Non-Cancerous	GDSC	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation altering degron motif	0.719
p.R296C	ACH-002358	Non-Cancerous	CCLE	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation altering degron motif	0.719
p.E310K	TCGA-BS-A0UV	UCEC	TCGA	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation rewiring degron network	0.1667
p.E310K	DO42793	UCEC	ICGC	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation rewiring degron network	0.1667
p.R313S	DO229032	LICA	ICGC	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation rewiring degron network	0.0833
p.P291S	DO220898	MELA	ICGC	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation rewiring degron network	0.1944
p.G288R	ACH-000923	Lymphoma	CCLE	RRAFLDLLL	DEG_APCC_DBOX_1	296:304	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc