DegronMD - Q70JA7(CHSY3)

CHSY3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A706V	TCGA-AX-A2HD	UCEC	TCGA	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.1389
p.A706V	DO42608	UCEC	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.1389
p.T712I	TCGA-BR-8059	STAD	TCGA	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.3056
p.T712I	DO38443	STAD	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.3056
p.E725K	TCGA-DK-A6AW	BLCA	TCGA	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.1389
p.E725K	DO48566	BLCA	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.1389
p.L713S	DO222752	COCA	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation altering degron motif	0.7667
p.L721F	DO228743	LICA	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.25
p.A704V	DO231893	LINC	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.0833
p.D720E	DO230451	UTCA	ICGC	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.2778
p.A706S	ACH-000786	Lymphoma	CCLE	LLLFCD	LIG_APCC_ABBA_1	713:718	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc