DegronMD - Q712K3(UBE2R2)

UBE2R2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E236G	TCGA-AP-A1DK	UCEC	TCGA	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.6087
p.E236G	DO42033	UCEC	ICGC	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.6087
p.E237D	TCGA-AX-A2IN	UCEC	TCGA	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.5647
p.E237D	DO42328	UCEC	ICGC	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.5647
p.S238L	TCGA-QS-A5YQ	UCEC	TCGA	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.8778
p.S238L	DO49073	UCEC	ICGC	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.8778
p.A225S	DO229045	LICA	ICGC	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation rewiring degron network	0.1389
p.S238T	SIDM00867	Glioblastoma	GDSC	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.7116
p.S238T	ACH-000863	Brain Cancer	CCLE	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.7116
p.S238T	DBTRG-05MG	central nervous system	COSMIC	DSGNEES	DEG_SCF_TRCP1_1	232:238	Mutation altering degron motif	0.7116

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*NOTE: the Kaplan plots were collected from OncoLnc