DegronMD - Q7L4I2(RSRC2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R114H	TCGA-AP-A1DV	UCEC	TCGA	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation rewiring degron network	0.1944
p.R114H	DO43186	UCEC	ICGC	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation rewiring degron network	0.1944
p.R114C	TCGA-FI-A2D6	UCEC	TCGA	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation rewiring degron network	0.1944
p.R114C	DO43867	UCEC	ICGC	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation rewiring degron network	0.1944
p.D96H	TCGA-ZF-AA53	BLCA	TCGA	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation rewiring degron network	0.1111
p.D96H	DO219096	BLCA	ICGC	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation rewiring degron network	0.1111
p.G108D	SIDM00846	Cervical Carcinoma	GDSC	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation altering degron motif	0.7198
p.G108D	ACH-001086	Cervical Cancer	CCLE	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation altering degron motif	0.7198
p.G108D	HeLa	cervix	COSMIC	SSENGE	DEG_Kelch_Keap1_1	104:109	Mutation altering degron motif	0.7198

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons