DegronMD - Q7L5N7(LPCAT2)

LPCAT2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I230F	TCGA-A6-6780	COAD	TCGA	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.0556
p.I230F	DO10244	COAD	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.0556
p.S208T	TCGA-D8-A1XK	BRCA	TCGA	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.1389
p.S208T	DO4749	BRCA	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.1389
p.W212L	TCGA-DA-A1I1	SKCM	TCGA	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.25
p.W212L	DO37966	SKCM	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.25
p.R226C	TCGA-DA-A95X	SKCM	TCGA	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.1667
p.R226C	DO219480	SKCM	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.1667
p.S208P	TCGA-FI-A2D6	UCEC	TCGA	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.1389
p.S208P	DO43867	UCEC	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.1389
p.W212C	DO229045	LICA	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.25
p.T206I	DO231127	LUSC	ICGC	ILVFPE	LIG_APCC_ABBA_1	215:220	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc