DegronMD - Q7RTY8(TMPRSS7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R3C	TCGA-A5-A2K5	UCEC	TCGA	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation altering degron motif	0.8301
p.R3C	TCGA-CA-6718	COAD	TCGA	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation altering degron motif	0.8301
p.R3C	TCGA-EI-6917	READ	TCGA	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation altering degron motif	0.8301
p.L10F	TCGA-AZ-4315	COAD	TCGA	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation rewiring degron network	0.2222
p.E12K	TCGA-EO-A22X	UCEC	TCGA	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation rewiring degron network	0.1667
p.D14Y	DO46779	PAEN	ICGC	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation rewiring degron network	0.1111
p.I7T	SIDM00145	T-Lymphoblastic Leukemia	GDSC	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation rewiring degron network	0.3056
p.I7T	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation rewiring degron network	0.3056
p.R3L	SIDM00755	Non-Small Cell Lung Carcinoma	GDSC	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation altering degron motif	0.8428
p.R3L	NCI-H1793	lung	COSMIC	DKENS	DEG_APCC_KENBOX_2	2:6	Mutation altering degron motif	0.8428

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons