DegronMD - Q7Z3J2(VPS35L)

VPS35L

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V154M	SIDM00167	Head and Neck Carcinoma	GDSC	VRTRLEELD	DEG_APCC_DBOX_1	158:166	Mutation rewiring degron network	0.2222
p.V163A	LS-180	large intestine	COSMIC	VRTRLEELD	DEG_APCC_DBOX_1	158:166	Mutation altering degron motif	0.6936
p.I162N	Sarc9371	bone	COSMIC	VRTRLEELD	DEG_APCC_DBOX_1	158:166	Mutation altering degron motif	0.728
p.R159Q	TE-4	oesophagus	COSMIC	VRTRLEELD	DEG_APCC_DBOX_1	158:166	Mutation altering degron motif	0.7329
p.G151R	TE-4	oesophagus	COSMIC	VRTRLEELD	DEG_APCC_DBOX_1	158:166	Mutation rewiring degron network	0.1389
p.E164A	MC-CAR	haematopoietic and lymphoid tissue	COSMIC	VRTRLEELD	DEG_APCC_DBOX_1	158:166	Mutation altering degron motif	0.659

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*NOTE: the Kaplan plots were collected from OncoLnc