DegronMD - Q7Z3K6(MIER3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A124G	TCGA-13-2061	OV	TCGA	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.25
p.D126N	TCGA-34-2600	LUSC	TCGA	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.3056
p.P141S	TCGA-AX-A05Z	UCEC	TCGA	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.0833
p.P141H	TCGA-D3-A2JL	SKCM	TCGA	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.0833
p.V136L	DO48576	BLCA	ICGC	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.2222
p.E134Q	DO3001	BRCA	ICGC	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.2778
p.E140K	DO233693	GACA	ICGC	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.1111
p.D131N	DO44623	LGG	ICGC	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation altering degron motif	0.6932
p.V136I	DO38404	STAD	ICGC	LTPSVT	DEG_SCF_FBW7_1	127:132	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons