DegronMD - Q7Z6K5(ARPIN)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A127V	SIDM00128	Head and Neck Carcinoma	GDSC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.1944
p.A127V	JHU-011	upper aerodigestive tract	COSMIC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.1944
p.A139V	SIDM00660	Colorectal Carcinoma	GDSC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.2778
p.A139V	SIDM00869	Non-Cancerous	GDSC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.2778
p.D135N	SIDM00998	Glioblastoma	GDSC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5821
p.D135N	SIDM01554	Mesothelioma	GDSC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5821
p.A123T	OVCAR-4	ovary	COSMIC	LTPDHT	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons