DegronMD - Q7Z7K6(CENPV)

CENPV

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S100R	DO228952	LICA	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation altering degron motif	0.7427
p.F97L	DO229019	LICA	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation rewiring degron network	0.2778
p.T98N	DO229022	LICA	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation blocking phosphorylation signal	0.75
p.P89T	DO229037	LICA	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation rewiring degron network	0.0556
p.M106I	DO50094	LUSC	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation rewiring degron network	0.3056
p.R90W	DO38404	STAD	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation rewiring degron network	0.0833
p.L106P	DO229268	THCA	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation rewiring degron network	0.3056
p.G99V	DO42472	UCEC	ICGC	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation altering degron motif	0.7532
p.T100M	ACH-000941	Endometrial/Uterine Cancer	CCLE	PATPTSS	DEG_SCF_FBW7_1	99:105	Mutation altering degron motif	0.7423

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc