DegronMD - Q86SE5(RALYL)

GO - Biological processes (BP):

GO - Molecular function (MF): identical protein binding [GO:0042802]; RNA binding [GO:0003723]

GO - Cellular component (CC): nucleoplasm [GO:0005654]; nucleus [GO:0005634]

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Show entries

Search:

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R164C	TCGA-4Z-AA89	BLCA	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8301
p.R164C	TCGA-LN-A49Y	ESCA	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8301
p.R164C	TCGA-T3-A92N	HNSC	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8301
p.R164H	TCGA-27-2527	GBM	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8244
p.R164H	TCGA-L5-A43J	ESCA	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8244
p.T166I	ACH-001669	Leukemia	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8189
p.T166I	ACH-002238	Leukemia	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8189
p.T166I	GR-ST	haematopoietic and lymphoid tissue	COSMIC	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.8189
p.R164G	TCGA-L9-A7SV	LUAD	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.7568
p.V166I	TCGA-BR-8682	STAD	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.7076
p.P163S	TCGA-FS-A1ZQ	SKCM	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation altering degron motif	0.6752
p.P161L	TCGA-DA-A1HY	SKCM	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167L	DO228971	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167C	DO220894	MELA	ICGC	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167H	ACH-000320	Pancreatic Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167H	ACH-000412	Colon/Colorectal Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167H	ACH-000660	Lymphoma	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167H	ACH-000776	Brain Cancer	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.R167H	ACH-001127	Leukemia	CCLE	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.3056
p.P168L	TCGA-AP-A1DV	UCEC	TCGA	AVTTT	DEG_SPOP_SBC_1	162:166	Mutation rewiring degron network	0.2778

Showing 1 to 20 of 57 entries

Previous1 2 3Next

No resistance data available for this Degron.

Kaplan plot for RALYL in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RALYL

UniProt ID: Q86SE5

Entrez ID: 138046

Protein name: RNA-binding Raly-like protein (hRALYL) (Heterogeneous nuclear ribonucleoprotein C-like 3) (hnRNP core protein C-like 3)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

No resistance data available for this Degron.

Kaplan plot for RALYL in