DegronMD - Q86T20(SMIM29)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L86P	SIDM00582	Pancreatic Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM00608	Plasma Cell Myeloma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM00548	Squamous Cell Lung Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM00567	Other Solid Cancers	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01217	Other Blood Cancers	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM00579	Neuroblastoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01612	Endometrial Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01617	Endometrial Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01335	Kidney Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM00168	Head and Neck Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01770	Gastric Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01779	Gastric Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.L86P	SIDM01434	Hepatocellular Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1389
p.C83R	SIDM00400	B-Cell Non-Hodgkin's Lymphoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.0556
p.C83R	SIDM00638	Cervical Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.0556
p.P107S	SIDM00068	Colorectal Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1667
p.P107S	GEO	large intestine	COSMIC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1667
p.P107A	SIDM01451	Pancreatic Carcinoma	GDSC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1667
p.P87S	GEO	large intestine	COSMIC	KRMPLLDVK	DEG_APCC_DBOX_1	93:101	Mutation rewiring degron network	0.1667

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SMIM29

UniProt ID: Q86T20

Entrez ID: 221491

Protein name: Small integral membrane protein 29 (Protein LBH)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SMIM29 in