DegronMD - Q86UE8(TLK2)

TLK2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T740A	TCGA-A6-5665	COAD	TCGA	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0833
p.T740A	ACH-002179	Breast Cancer	CCLE	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0833
p.T740A	OCUB-M	breast	COSMIC	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0833
p.S748Y	TCGA-AX-A0J0	UCEC	TCGA	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.3056
p.A743V	TCGA-CK-4951	COAD	TCGA	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.1667
p.S741Y	TCGA-CN-6010	HNSC	TCGA	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.1111
p.S739A	TCGA-US-A774	PAAD	TCGA	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0556
p.T762A	SIDM00241	Breast Carcinoma	GDSC	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0833
p.T762A	OCUB-M	breast	COSMIC	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0833
p.S763F	ACH-000923	Lymphoma	CCLE	VSTSS	DEG_SPOP_SBC_1	749:753	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc