DegronMD - Q86UT8(CENATAC)

CENATAC

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A184V	TCGA-A5-A0GP	UCEC	TCGA	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation rewiring degron network	0.1667
p.A184V	DO41109	UCEC	ICGC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation rewiring degron network	0.1667
p.P172S	TCGA-A5-A2K7	UCEC	TCGA	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation altering degron motif	0.5641
p.P172S	DO41271	UCEC	ICGC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation altering degron motif	0.5641
p.Q173P	DO233804	GACA	ICGC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation altering degron motif	0.5924
p.P178S	DO229053	LICA	ICGC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation altering degron motif	0.6752
p.V169L	ACH-000971	Colon/Colorectal Cancer	CCLE	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation altering degron motif	0.5654
p.V169L	HCT-116	large intestine	COSMIC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation altering degron motif	0.5654
p.R167Q	ACH-002234	Head and Neck Cancer	CCLE	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation rewiring degron network	0.3056
p.R167Q	DOK	upper aerodigestive tract	COSMIC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation rewiring degron network	0.3056
p.R162Q	NK-92MI	haematopoietic and lymphoid tissue	COSMIC	SVLEPQAVPDP	DEG_COP1_1	168:178	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc