DegronMD - Q86UY5(FAM83A)

FAM83A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R13H	TCGA-DU-6392	LGG	TCGA	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation altering degron motif	0.7133
p.R13H	DO22237	LGG	ICGC	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation altering degron motif	0.7133
p.R26M	TCGA-EO-A3KX	UCEC	TCGA	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation rewiring degron network	0.1111
p.R26M	DO219774	UCEC	ICGC	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation rewiring degron network	0.1111
p.R23W	DO46542	OV	ICGC	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation rewiring degron network	0.1944
p.R26W	SIDM00989	Bladder Carcinoma	GDSC	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation rewiring degron network	0.1111
p.R26W	ACH-000802	Bladder Cancer	CCLE	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation rewiring degron network	0.1111
p.R26W	BFTC-905	urinary tract	COSMIC	IRKRLEDVK	DEG_APCC_DBOX_1	10:18	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc