DegronMD - Q86V87(FHIP2B)

FHIP2B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S507I	TCGA-AP-A051	UCEC	TCGA	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.25
p.S507I	DO42673	UCEC	ICGC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.25
p.D510N	TCGA-CQ-6221	HNSC	TCGA	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation altering degron motif	0.6932
p.D510N	DO14622	HNSC	ICGC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation altering degron motif	0.6932
p.F513L	TCGA-WS-AB45	COAD	TCGA	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation altering degron motif	0.587
p.F513L	DO51734	COAD	ICGC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation altering degron motif	0.587
p.S507R	DO48388	BLCA	ICGC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.25
p.A517T	DO234387	ESAD	ICGC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.2778
p.Y503N	SIDM00416	B-Cell Non-Hodgkin's Lymphoma	GDSC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.1389
p.Y503N	VAL	haematopoietic and lymphoid tissue	COSMIC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.1389
p.Y503C	SIDM01779	Gastric Carcinoma	GDSC	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.1389
p.Y503C	ACH-000761	Gastric Cancer	CCLE	DSGFQT	DEG_SCF_TRCP1_1	510:515	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc