DegronMD - Q86VQ6(TXNRD3)

TXNRD3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G73E	DO223732	CESC	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation substituting flanking lysine	0.1667
p.H56Q	DO229028	LICA	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.7582
p.H56Q	DO229035	LICA	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.7582
p.S71L	DO222908	MELA	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation rewiring degron network	0.1111
p.S71L	DO41542	UCEC	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation rewiring degron network	0.1111
p.G54E	DO220285	SARC	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation rewiring degron network	0.3056
p.V62A	DO42713	UCEC	ICGC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.6936
p.S72N	SIDM01314	Colorectal Carcinoma	GDSC	LRRHLVGLI	DEG_APCC_DBOX_1	55:63	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc