DegronMD - Q86WA8(LONP2)

LONP2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V647A	TCGA-BS-A0UF	UCEC	TCGA	PPMY	ITCH	640:643	Mutation rewiring degron network	0.2222
p.V647A	DO41488	UCEC	ICGC	PPMY	ITCH	640:643	Mutation rewiring degron network	0.2222
p.L638I	TCGA-CA-6718	COAD	TCGA	PPMY	ITCH	640:643	Mutation rewiring degron network	0.2778
p.R650H	TCGA-CM-6162	COAD	TCGA	PPMY	ITCH	640:643	Mutation rewiring degron network	0.1389
p.R650H	DO8479	COAD	ICGC	PPMY	ITCH	640:643	Mutation rewiring degron network	0.1389
p.E644D	TCGA-DD-AACQ	LIHC	TCGA	PPMY	ITCH	640:643	Mutation rewiring degron network	0.3056
p.E644D	DO52211	LIHC	ICGC	PPMY	ITCH	640:643	Mutation rewiring degron network	0.3056
p.E646V	TCGA-L7-A6VZ	ESCA	TCGA	PPMY	ITCH	640:643	Mutation rewiring degron network	0.25
p.E644K	SIDM00240	Cervical Carcinoma	GDSC	PPMY	ITCH	640:643	Mutation rewiring degron network	0.3056
p.E644K	ACH-002180	Cervical Cancer	CCLE	PPMY	ITCH	640:643	Mutation rewiring degron network	0.3056
p.E644K	OMC-1	cervix	COSMIC	PPMY	ITCH	640:643	Mutation rewiring degron network	0.3056
p.R650C	ACH-000574	Ovarian Cancer	CCLE	PPMY	ITCH	640:643	Mutation rewiring degron network	0.1389
p.R650C	FU-OV-1	ovary	COSMIC	PPMY	ITCH	640:643	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc