DegronMD - Q86WK6(AMIGO1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R5H	DO234410	ESAD	ICGC	MHPHRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7133
p.P7L	DO233156	GACA	ICGC	MHPHRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.3056
p.P15L	SIDM00946	T-Lymphoblastic Leukemia	GDSC	MHPHRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.0833
p.P15L	ACH-000981	Leukemia	CCLE	MHPHRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.0833
p.P15L	DND-41	haematopoietic and lymphoid tissue	COSMIC	MHPHRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons