DegronMD - Q86X53(ERICH1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D268H	TCGA-68-8251	LUSC	TCGA	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.A269P	TCGA-85-8666	LUSC	TCGA	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1667
p.A269P	DO45547	LUSC	ICGC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1667
p.G262R	TCGA-AY-6197	COAD	TCGA	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.6457
p.G262R	DO9956	COAD	ICGC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.6457
p.T259I	TCGA-B5-A1MX	UCEC	TCGA	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.7078
p.P258L	TCGA-DM-A1D6	COAD	TCGA	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.6471
p.V266F	TCGA-DS-A7WF	CESC	TCGA	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.25
p.V266F	DO49922	CESC	ICGC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.25
p.G261S	DO36969	READ	ICGC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.6993
p.P260L	SIDM01198	Burkitt's Lymphoma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.7582
p.P260L	ST486	haematopoietic and lymphoid tissue	COSMIC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation altering degron motif	0.7582
p.A253T	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.A253T	SIDM00309	Mesothelioma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.A253T	SIDM00808	Burkitt's Lymphoma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.A253T	SIDM01752	Pancreatic Carcinoma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.A253T	SIDM01254	Burkitt's Lymphoma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.A253T	ACH-000729	Lung Cancer	CCLE	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.1944
p.E249K	SIDM00699	Small Cell Lung Carcinoma	GDSC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.0833
p.E249K	ACH-001138	Lung Cancer	CCLE	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.0833
p.E249K	NCI-H2141	lung	COSMIC	PTPAGE	DEG_SCF_FBW7_2	258:263	Mutation rewiring degron network	0.0833

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ERICH1

UniProt ID: Q86X53

Entrez ID: 157697

Protein name: Glutamate-rich protein 1

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ERICH1 in